Children's Oncology Group (COG) Cell Culture and Xenograft Repository

Requesting Cell-lines

List of Available Leukemia Lines

How to Request a Cell Line:

(1) Select the cell line(s) by clicking each check box next to the cell line name.
(2) Fill out the institutional or commercial/industry information at the bottom of the page.
(3) Attach a fully signed MTA (including Attachment A)
(4) Attach any additional documents required for your request (i.e. a justification for any request over 5 cell lines total)
(5) Click Submit.

For all other questions regarding your request and/or MTA, please visit our FAQ page.


All cell lines were established in 20% O2 unless otherwise noted. Cell lines ending in "h" designates cell line was established in hypoxic conditions (5% O2 tension).

Please visit the COGcell.org website frequently, as cell line data is continually being updated and new cell lines are added.


Leukemia Cell Lines Request Form

Request Cell Line Disease Diagnosis Gender Age (Years) Phase of Therapy1 Site of Specimen DT5 (hours)
COG-LL-317* Leukemia T-cell ALL M 1.7 PD Bone marrow 30-40
COG-LL-317h* Leukemia T-cell ALL M 1.7 PD Bone marrow 19-20
COG-LL-319h Leukemia Pre-B ALL F 13 Dx Bone marrow 50-62
COG-LL-329h Leukemia T-cell ALL     Dx Bone marrow  
COG-LL-332h Leukemia T-cell ALL M 10 PD Bone marrow 30-34
COG-LL-355h Leukemia Pre-B ALL     Dx Bone marrow  
COG-LL-356h Leukemia Pre-B ALL     Dx Bone marrow  
COG-LL-384h Leukemia T-cell ALL     PD Bone marrow  

1 - Phase of therapy for the patient at the time the specimen used to derive the cell line was obtained
Dx (Diagnosis): cell lines derived from samples of patients prior to treatment
PD (Progressive Disease): cell lines derived from samples of patients who relapsed after chemotherapy
PD-BMT: cell lines derived from samples of patients who relapsed after chemotherapy and bone marrow transplantation
PD-PM: cell lines derived from samples of post-mortem patients who relapsed after chemotherapy

5 - Doubling Time

For details on all the cell lines see:

Kang MH, Smith MA, Morton CL, Nino Keshelava N, Houghton PJ, Reynolds CP: National Cancer Institute Pediatric Preclinical Testing Program: Model description for in vitro cytotoxicity testing. Pediatr Blood Cancer 56:239-49, 2011.

* - NCI PPTP Cell Lines

Shipping and Contact Information

Please enter your name:

Please enter your telephone number:

Please enter your complete shipping address:

Please enter your email address:

Please enter your Institution:

Please provide the name of your courier (eg. FedEx, Airborne, World Courier) if available:
(We cannot ship via UPS or DHL at this time. Please contact us with questions or concerns.)

Please provide your FedEx or other courier account number (if available):

If you are requesting more than 5 cell lines:
Who should review the proposal? (Please select one)

The Disease Committee (for requests of material of a single disease)

The Biology and Translational Research Committee (for requests of material from multiple diseases)

If you are requesting 5-15 cell lines, upload a < 1 page description of research and justification for the lines.

(PDF format only; maximum allowed file size is 2 megabytes)

If you are requesting more than 15 lines, upload a full COG biology specimen application form.

(PDF format only; maximum allowed file size is 2 megabytes)

Upload your COG Specimen Transfer Agreement:

(PDF format only; maximum allowed file size is 2 megabytes)

You can also FAX this form to 806-743-2691 if you have difficulty uploading it.

Do you have any special requests or comments? If so, please enter them here.